ORAL MEDICINE AND The virus’s diameter is 120nm with a lipid bilayer and a core RNA genome. conformational structure occurs in the structure and the process of entry into the virus cell begins [35,36]. STRUCTURE The structure of a virus and how it infects a cell. Viruses are extremely small, approximately 20 - 400 nanometers in diameter. In Viruses, Nucleic Acids, and Cancer, 17th Annual Symposium on Fundamental Cancer Looks like you’ve clipped this slide to already. Clipping is a handy way to collect important slides you want to go back to later. WHAT IS A VIRUS? Now customize the name of a clipboard to store your clips. 1796 Jenner developed smallpox vaccine 1915- Descriptions of many viruses 1901 Mosquito transmission of YFV 1949 PV grown in cultured cells 1985 Structure of poliovirus to 2.9Å FIGURE 1.1 Timeline of development of virology. As of this date, Scribd will manage your SlideShare account and any content you may have on SlideShare, and Scribd's General Terms of Use and Privacy Policy will apply. Structure of a Virus A virus contains nucleic acid (DNA or RNA) Surrounded by a protective coat (capsid) Spread of the virus - also known as obligate parasites Viruses can be spread by touching, body fluids, HIV aerosols (sneezing, coughing etc. Viruses have no . Virus Structure: A virus is an infectious non-living particle that cannot survive on its own.It is considered to be non-living because it cannot exist purely by itself. Do you have PowerPoint slides to share? A virus particle, also known as a virion, is essentially nucleic acid (DNA or RNA) enclosed within a protein shell or coat. They consist a short stretch (a few hundred nucleobase) of highly complementary circular single stranded RNA without protein coat with molecular weight between 1,07,000 and 1,27,000. Structure of Viruses A unique protein coat: shape of the protein allows the coat to attach to, or lock onto, specific host cells Example: HIV attach T -4 cells *Genetic material is inside of the virus (DNA or RNA) Hepatitis B is a viral infection that attacks the … Viruses. Viral nucleocapsids come in two basic shapes, although the overall appearance of a virus can be altered by the presence of an envelope, if present. See our User Agreement and Privacy Policy. microscopic infectious agents that can only replicate inside a host cell The virion structure consists of an outer envelope, the core, nucleoprotein and a nucleocapsid. Alfred Pasieka/Science Photo Library/Getty Images. ), e.g. For example, the host cell may be “biochemically exhausted,” and it may disintegrate, thereby releasing the virions. Certain proteins on the virus particle must fit certain receptor sites on the particular host's cell surface. If you continue browsing the site, you agree to the use of cookies on this website. Virus structure: classification: replication, BEST PRACTICES IN DIAGNOSTIC MICROBIOLOGY, JOURNAL CLUBin medicinepreparation and presentation, CRISIS IN INDIAN MEDICAL EDUCATION Time to Verify, WHONET DOCUMENTATION IN ANTIBIOTIC POLICY. Now customize the name of a clipboard to store your clips. Pneumonia Bites, e.g. VIRUS ; An enveloped virus, the outer layer is a lipid membrane which is taken from the host cell. Virus are very small infectious agents with size ranging from 20-300nm in diameter. • ASHISH RANGHANI I. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. cytoplasm. What a virus is. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. 6 1. All DNA virus, Retro virus and some tumor causing RNA virus replicates through ds DNA as intermediates. Replication of a DNA virus is shown in (1); replication of an RNA virus is displayed in (2). Comparison with influenza virus HA suggests that the rod-like structure in the middle likely represents the six-helix bundle formed by HR-N and HR-C, whereas the globular structures at the two ends likely correspond to the regions N-terminal to HR-N and between HR-N and HR-C, respectively (Figures 1c and 6c). We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Some filoviruses have a total length of up to 1400 nm; their diameters are only about 80 nm. GDCH Structure: Before understanding how it spreads, it is very important to understand the general structure of the coronavirus. Protein_id "YP_009725301.1". Clipping is a handy way to collect important slides you want to go back to later. April 20, 2010 Acharya Tankeshwar Structure of Virus 0. … (1963) "Structure and Assembly of Regular Virus Particles." If you continue browsing the site, you agree to the use of cookies on this website. Viral replication: lytic vs lysogenic. For the release of new viral particles, any of a number of processes may occur. This is why it does NOT belong to any . It requires a host cell to replicate itself and uses the host cell replication and protein synthesis machinery to create progeny of its own. Virus particles are elegant assemblies of protein, nucleic acid, and in some cases lipids. Virus Structure. Virus structure 1. DATE- 27/07/2016. Are viruses dead or alive? • The outer shell of this virus is approximately 80 nm in diameter & the inner shell (core) about 60 nm. VIRUS STRUCTURE • ASHISH RANGHANI • PG PART 2 • GDCH, AHMEDABAD UNDER GUIDANCE OF DR. J.S SHAH PROFESSOR AND HEAD ORAL MEDICINE AND RADIOLOGY GDCH DATE- 27/07/2016 2. Classification of virus on the basis of host range: 1. Structure of Influenza virus Influenza virion are usually spherical (diameter 80-110 nm). Dr.T.V.Rao MD 12 13. • The structure of the bluetongue virus core was recently reported & represents the largest structure yet determined to atomic resolution (3.5 Å). Difference Between DNA & RNA Virus 5. vs. Cleaves viral polyprotein. Dr.T.V.Rao MD 1. nucleus, no . UNDER GUIDANCE OF • When a virus infects a cell, nucleic acid must be uncoated and gain access to metabolic machinery of cell. All RNA virus except Reo virus and tumor causing RNA viruses. Dental College and Hospital, Ahmedabad. • The structure of the bluetongue virus core was recently reported & represents the largest structure yet determined to atomic resolution (3.5 Å). Viruses are non-cellular entities so they are also called as particles. It affects humans as … The PowerPoint PPT presentation: "The Structure & Complexity of Virus Genomes" is the property of its rightful owner. Turnip yellow mosaic virus; VACV, Vaccinia virus; YFV, Yellow fever virus. So they are also called as obligate intracellular parasites. You can change your ad preferences anytime. See our User Agreement and Privacy Policy. WORK PLACE CHALLENGES - WE CAN FIGHT BACK? The envelope of the virus is formed when the virus is exiting the cell via budding, and the infectivity of these viruses is mostly dependent on the envelope. Virus replication through ds DNA intermediate: Eg. The virus is carried by multimamate rats of the genus Mastomys and transmitted to humans via the inhalation of the rat’s urine (the virus is carried by primary aerosols), contact with the rat’s urine, feces, saliva, or respiratory secretions, or ingestion of contaminated foods. 5. Some sources state that it affects 2-3 million people yearly (killing 5,000-10,000), while others maintain that it affects only 100,000-300,000. viruses are much smaller than bacteria. If you continue browsing the site, you agree to the use of cookies on this website. Retroviruses. Structure of Viroids: Structure of viroid was first shown directly by electron microscope, Viroid’s are small, circular, single stranded RNA molecules. RADIOLOGY Hepatitis B Virus- Structure, Epidemiology, Symptoms, Pathogenesis, Diagnosis, Treatment and Vaccines. Th is process with endocytosis is dependant of pH through the receptor [37-40]. About 5 percent of the length of the virion is depicted. This is the currently selected item. Virus structure and classification. PROFESSOR AND HEAD VIRUS STRUCTURE A virus is an infectious agent made up of nucleic acid (DNA or RNA) wrapped in a protein coat called a capsid.. See our Privacy Policy and User Agreement for details. A virus is a chain of nucleic acids (DNA or RNA) which lives in a host cell, uses parts of the cellular machinery to reproduce, and releases the replicated nucleic acid chains to infect more cells. Practice: Virus structure and reproductive cycle questions. ADVERTISEMENTS: In this article we will discuss about the structure and replication of pox viruses. Dr.T.V.Rao MD Most viruses that have been studied have a diameter between 20 and 300 nanometers. As of this date, Scribd will manage your SlideShare account and any content you may have on SlideShare, and Scribd's General Terms of Use and Privacy Policy will apply. Aft er entering the cytoplasm, the virus particle releases the RNA genome. ; Inserted into the lipid membrane are ‘spikes’, about 10 nm long, which are glycoproteins, known as HA (hemagglutinin), and NA (neuraminidase). If you continue browsing the site, you agree to the use of cookies on this website. Definition 3. The PowerPoint PPT presentation: "VIRUS STRUCTURE" is the property of its rightful owner. 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